Helps reduce the symptoms of irritable bowel syndrome in adults

The wall of the digestive tract is selectively permeable. It allows nutrients to pass through while forming a barrier between the contents of the intestine and the rest of the body. This barrier is not a simple partition: it is made up of cells joined together, covered by a layer of mucus, and colonized by a microbiota. GI Matrix was designed around this architecture, with one ingredient associated with each level.

L-glutamine, 4.5 g per scoop. It is the most abundant amino acid in the human body and the preferred energy source of enterocytes, the cells lining the small intestine. It is also a precursor to glutathione. Muscle glutamine stores drop during periods of major physical stress, convalescence, or intensive training, which explains why supplementation is primarily studied in these contexts. The dose is substantial: 9 g per day at the full dosage, in the range of what is used clinically rather than a token dose.

Zinc L-carnosine, 37.5 mg per scoop. A molecule that combines elemental zinc with carnosine, a dipeptide made up of beta-alanine and histidine. This combination behaves differently from an ordinary zinc salt: it adheres longer to the digestive mucous membranes before dissociating, making it the most extensively studied ingredient in the formula from a gastroprotective standpoint. Each scoop provides 8.5 mg of elemental zinc, or 17 mg per day at the full dosage.

N-acetylglucosamine, 500 mg per scoop. Mucin is the layer of mucus that covers the intestinal epithelium and separates it from the microbiota. N-acetylglucosamine is the basic building block from which the body produces it. Notably for product accessibility: the N-acetylglucosamine in GI Matrix comes from biosynthesis by Bacillus subtilis, rather than from shellfish shells like most glucosamines available on the market.

Bacillus coagulans IS-2, 1 billion CFU per scoop. A spore-forming probiotic. Unlike Lactobacillus and Bifidobacterium, this bacterium travels in spore form, a dormant state that withstands temperature fluctuations and stomach acidity. Germination occurs in the small intestine. Practical consequence: the powder can be stored at room temperature and does not require refrigeration.

Powder rather than capsules. At 4.5 g of glutamine per serving, a capsule format was not feasible. The powder dissolves in 1 to 2 cups of water or juice, with no added flavour and only a touch of monk fruit extract. The 311 g container provides 30 days at the full dosage.

Gluten-free, soy-free, dairy-free.

Recommended use Helps reduce the symptoms of irritable bowel syndrome in adults with this condition: abdominal discomfort, pain intensity, bloating, and the sensation of incomplete evacuation. Helps relieve symptoms associated with functional constipation. Helps maintain digestive and immune system health following periods of physical stress. Source of probiotics that may promote a healthy intestinal microbiota.